25 October 2017
Session Category : Genetics - Omics...
I am a bioinformatics with primary interest in cell-specific transcription regulation. The Glass laboratory focuses on deciper the function of enhancers in macrophages and my substaintal eduction provide me with the possibilities to understand the currently established biological systems as well as to analyze data with well-established methods and further develop new approaches for the analysis. I am now actively working on the analysis of genome-wide deep-sequencing methods in several inbred mouse strains to understand the regulation of transcription by linage-depenendent and signal-dependent transcription factors in response to inflammatory signals. My major goal in this project is to gain a fundamental understanding of transcription regulation by binding of transcription factors on enhancers and the effect of these factors for cell-specificity.