Bernard Thorens
Université de Lausanne, Switzerland


Biography

Bernard Thorens is Professor at the Center for Integrative Genomics of the University of Lausanne. He graduated in biochemistry and obtained his PhD from the university of Geneva and did a postdoctoral training at the Whitehead Institute for Biomedical Research at MIT. He was the first to molecularly clone and characterize the glucose transporters Glut2 and the receptor for the gluco-incretin hormone GLP-1. His present research focuses on the identification of the central nervous glucose sensing pathways that control glucose homeostasis and feeding behavior. His laboratory also investigates novel signaling pathways controlling adult pancreatic beta-cell functional plasticity in response to gluco-incretin hormones action, nutrients, and metabolic stress. These regulatory pathways are being targeted for the treatment of diabetes. His work is supported by grants from the Swiss National Science Foundation, the European Innovative Medicine Initiative, and ERC grants.